recent advances in nanoformulations for co-delivery of curcumin and chemotherapeutic drugs
Authors
abstract
the application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. in recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. on the other hand, encapsulation of drugs into nanoparticles (nps) can improve solubility of hydrophobic drug; circulation time in blood and the residence at the pathological site by enhance permeation and retention (epr) effect. it has been shown that curcumin (cur) has wide range of pharmacological activities against many diseases such as cancer. cur has been demonstrated to be a potent chemosensitizer that can induce additive or synergistic effects with chemotherapeutic drugs against different cancer cell lines. recently, various types of nanocarriers have been investigated for cur. in this review, different co-formulations containing cur and chemotherapeutic drugs used in cancer therapy are discussed with emphasis on their pharmaceutical properties.
similar resources
Recent advances in nanoformulations for co-delivery of curcumin and chemotherapeutic drugs
The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...
full textRecent advances in nanoformulations for co-delivery of curcumin and chemotherapeutic drugs
The application of chemotherapy in cancer treatment has been limited due to cause side effects such as toxicity against normal cells and drug resistance. In recent years, numerous studies have been focused on using natural products with chemotherapeutic drugs to enhance therapeutic efficiency and reduce cytotoxicity. On the other hand, encapsulation of drugs into nanoparticles (NPs) can improve...
full textA Review of the Recent Advances and Application of 3D Printing in Pharmacy and Drug Delivery
Throughout human history, the most valuable inventions have been those that, even decades after their initial introduction, affected the lives of people around the world. 3D printers similar to steam engines, light bulbs, and the World Wide Web are thought to be among the inventions that will revolutionize the future of different industries. This technology is generally introduced as the manuf...
full textNanocarrier-mediated co-delivery of chemotherapeutic drugs and gene agents for cancer treatment
The efficacy of chemotherapeutic drug in cancer treatment is often hampered by drug resistance of tumor cells, which is usually caused by abnormal gene expression. RNA interference mediated by siRNA and miRNA can selectively knock down the carcinogenic genes by targeting specific mRNAs. Therefore, combining chemotherapeutic drugs with gene agents could be a promising strategy for cancer therapy...
full textNanoformulations of curcumin: an emerging paradigm for improved remedial application
Curcumin is a natural polyphenol and essential curcuminoid derived from the rhizome of the medicinal plant Curcuma longa (L.) is universally acknowledged as "Wonder drug of life". It is a vital consumable and restorative herb, commonly keened for several ailments such as cancer, arthritis, pain, bruises, gastrointestinal quandaries, swelling and much more. Despite its enormous curative potentia...
full textMy Resources
Save resource for easier access later
Journal title:
nanomedicine journalجلد ۴، شماره ۱، صفحات ۱-۷
Keywords
Hosted on Doprax cloud platform doprax.com
copyright © 2015-2023